As part of its collaboration with the Cabinet cantonal des estampes, the Fondation William Cuendet & Atelier Saint-Prex regularly lends works from its collections to outside institutions for exhibitions and other projects. The Foundation also designs and organizes many of its own exhibitions. In keeping with its two-pronged mission and with the varied personalities represented on board (including artists, collectors, writers and art historians), these projects relate directly both to the works in its collections and to the concerns of the artists working at the Atelier de Saint-Prex.
In 1977, the year of its founding, the Fondation William Cuendet & Atelier Saint-Prex presented an exhibition of its collection as well as a focused show of works by Dürer and Rembrandt at the Musée de Pully. In 1981, in collaboration with the Parisian collection of André Jammes, the Foundation presented The Origin of Engraved Photography at the Musée de l'Elysée, an exhibition investigating the aquatint technique and the vanished secrets of heliogravure—two abiding interests of the Atelier's artists. Those themes would be taken up again a few years later in an exhibition at the Palais de Tokyo in Paris. The study of heliogravure, a printing process closely linked to the development of photography, would be further advanced by an exhibition entitled Graver la lumière (Engraving Light), presented during the winter of 2002-2003 at the Musée Jenisch in Vevey.
Over the years, the Fondation has presented and contributed to retrospectives devoted to many of the printmakers close to the Atelier, including Albert-Edgar Yersin, Henry Bischoff, Gérard de Palézieux, Ilse Lierhammer, Pietro Sarto, Edmond Quinche, Urs and Jon Goodman. In 1996 it organized a major scholarly exhibition that investigated three-colour printmaking: Anatomy of Colour: L'invention de l'estampe en couleurs (Anatomy of Colour: The Invention of the Colour Print). Jointly organized by the Fondation, the members of the Atelier de Saint-Prex and the Bibliothèque nationale de France, the exhibition was awarded the Prix Estampa for the best printmaking exhibition of the year. Accompanied by a major catalogue written by its two curators, Maxime Préaud and Florian Rodari, Anatomy of Colour then travelled to the Olympic Museum in Lausanne.
In 2007, to celebrate the Fondation's thirtieth anniversary, the board of trustees presented an exhibition of highlights from its collection, bringing together around one hundred emblematic works of any date or theme. Between 2010 and 2012, these works travelled to several venues throughout in Spain under the title Durero a Morandi. In 2017, a large exhibition entitled Impressions fortes, illustrating the collection’s richness and variety, took place at the Musée de Lodève. Meanwhile the collection had recently been enriched by the significant additions of works by two French portraitists of the seventeenth century, Robert Nanteuil and Claude Mellan. To celebrate these major acquisitions, curators Florian Rodari and Catherine McCready organized two successive exhibitions accompanied by scholarly catalogues: Robert Nanteuil: graveur du roi (2013) and Claude Mellan: L'écriture de la méthode (2015-2016).
More recently, in Paris (2019) and at the Musée Jenisch in Vevey (2020), a major exhibition organized with the Fondation Custodia celebrated the work of the painter, printmaker and collector Gérard de Palézieux. In summer 2023, the Fondation presented its collection at the Musée Marmottan, Paris. Reprising the title Graver la lumière (Engraving Light), this latest exhibition was accompanied by a catalogue.